trefoil factors initiate mucosal healing
| PAG Title | trefoil factors initiate mucosal healing |
| PAG ID | WAG001007 |
| Type | P |
| Source Link |  BioCarta |
| Publication Reference | NA |
| PAG Description | Maintaining the integrity of the gastrointestil tract despite the continual presence of microbial flora and injurious agents is essential. Epithelial repair requires restitution and regeneration. During restitution, epithelial cells spread and migrate across the basement membrane to re-establish surface-cell continuity, a process that is independent of cell proliferation. Epithelial continuity depends on a family of small abundant secreted proteins, the trefoil factors (TFFs). |
| Species | Homo sapiens |
| nCoCo Score | 2,921 |
| Base PAG ID | WAG001007 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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